Natural Dietary Treatments for Fibroids

The same diet that helps regulate hormones in women may also reduce exposure to endocrine-disrupting pollutants.

Fibroids are the most common benign tumors in women. They can grow to a foot in diameter and affect the majority of women before they hit menopause. Although fibroids tend to be asymptomatic, when symptoms do occur, they tend to manifest as heavy menstrual bleeding—so much so that women may get anemic and experience a lot of pain. So, what can women do? I discuss this in my video The Best Diet for Fibroids.

Up to half go into surgery and get their entire uterus removed. “Although hysterectomy is generally considered a safe operation, complications occur in a significant proportion of patients” and, obviously, you can’t have kids any more. The alternative is a variety of hormone-modulating drugs, which can shrink the fibroids and provide relief, but many of these drugs have significant side effects, like bone loss, so you really don’t want to be taking them for more than a few months. What’s the bottom line? “There is currently no evidence to support the routine use of medical treatment in women with uterine fibroids.” No wonder many women turn to “complementary and alternative treatments…including exercise, diet, herbs, and acupuncture.”

Women who exercise seven or more hours a week do seem to have lower risk of having fibroids than women who exercise less than around 20 minutes a day, but exercise has never been put to the test for treating fibroids. Likewise, to date, there isn’t a single randomized controlled trial of acupuncture for the treatment of fibroids to help guide us. 

In terms of herbs, there are two Asian herbal preparations that show promise—a five-herb combo called Guizhi Fuling and a Malaysian ten-herb formula that contains “secret ingredients” that must not be that secret since they’re just listed in the study, as you can see at 1:50 in my video—and they seemed to work as well as a leading drug. The problem is that traditional Asian herbal remedies may contain a few extra ingredients, like arsenic, mercury, and lead, which have been detected in most of the samples tested from Asian market and health food store shelves, and not just a little. Some, apparently, had really toxic amounts. So, these two Asian herbal preparations “may reduce fibroid size, but there is insufficient evidence to support the efficacy or safety of these treatments.” And, certainly, don’t try to apply caustic herbs internally, as this can lead to scarring, stenosis, and ulceration.

Well, what about diet? In one of the largest studies of diet and fibroids, fibroid tumors were “associated with beef and ham consumption, whereas high intake of green vegetables seems to have a protective effect.” The researchers figured that the “association between levels of estrogen, diet, and breast and endometrial [uterine lining] cancers also may help us understand” why. Indeed, “[f]or breast and endometrial cancers, a direct association with the frequency of consumption of meat and ham was observed…whereas protection was conferred by high intake of vegetables and fruits.” Thus, there may be these shared risk factors between estrogen-responsive malignant tumors, like breast cancer, and estrogen-responsive benign tumors, like fibroids.

We know the presence of fibroids seems to correlate with an increase in the amount of estrogens flowing through your body, for example, and that women eating vegetarian diets have significantly lower levels of excess estrogen. Researchers are using this knowledge to try to explain why there are lower rates of endometrial cancer—that is, lining-of-the-uterus cancer—and possibly breast cancer among vegetarian women, but it could also help explain the fibroid findings. “The incidence of breast cancer among vegetarian American women (Seventh Day Adventists) is 60 to 80 per cent of the incidence among American women in general, and the incidence among women in Africa and Asia is even lower.” Why might vegetarian women have lower estrogen levels? A famous study in the New England Journal of Medicine concluded that it was their “increased fecal output, which leads to increased fecal excretion of estrogen,” resulting in lower blood levels. Double the fecal output, in fact, as you can see at 4:07 in my video.

And, you can put it to the test. Maybe the same reason African-American women have more fibroids is the same reason they have worse breast cancer survival: too much estrogen in their bloodstream due to a less than optimal diet. So, researchers designed a study to see what would happen if they were switched to a more plant-based, higher fiber diet. Compared with the Caucasian women, the African-American women started out with much higher estrogen levels, again helping to explain their increased mortality from breast cancer. But, after they were put on a healthier diet, all of their levels came down, “suggest[ing] that a substantial reduction in breast cancer risk can be achieved” by adopting a diet centered around more whole plant foods. The same also appears to be true for fibroids, especially eating lots of cruciferous vegetables—broccoli, cabbage, and Chinese cabbage—as well as tomatoes and apples.

Women who underwent premature puberty, starting their periods before age 11, may also be at increased risk of fibroids later in life, and we know that higher childhood red meat intake is associated with earlier age of starting one’s period, though total protein and animal protein in general may contribute. For example, girls who eat meat tend to start their periods about six months earlier than vegetarian girls. Those who eat meat analogues like veggie burgers and veggie dogs start their periods nine months later on average, and a similar puberty normalizing influence was found with consumption of whole plants foods, such as beans. 

It could also be the endocrine-disrupting pollutants that build up the food chain. Researchers took samples of internal abdominal fat from women and found there appeared to be a correlation between the presence of fibroids with the levels of a number of PCBs in their fat. So, does that mean fish-eaters have higher risk of fibroids? Researchers did find a small increase in risk associated with the intake of long-chain omega-3 fats, mostly from “dark-meat fish consumption,” by which they meant fish like sardines and salmon. This could be because of “the endocrine-disrupting chemicals commonly shown in fish,” or it could just be a statistical fluke. It would be consistent with the increased risk seen among “sport-fish consumers.” 

Recognizing that diet and endocrine-disrupting persistent organic pollutants have been associated with a variety of gynecologic conditions, including fibroids, researchers looked at consumers of fish fished out of the Great Lakes and found a 20 percent increased risk for every ten years they had been eating the fish. In the most comprehensive study to date, researchers compared pollutant levels in fat samples from women with fibroids to fat liposuctioned out of women without fibroids. They didn’t just find higher levels of PCBs in fibroid sufferers, but also long-banned pesticides, like DDT and hexachlorocyclohexane, PAHs, which are polycyclic aromatic hydrocarbons formed when coal is burned, tobacco is smoked, and meat is grilled, as well as heavy metals, arsenic, cadmium, lead, and mercury. These levels correlated not only to fibroids, but also to seafood consumption or excess body fat. So, the researchers determined that “shedding excess weight and limiting seafood consumption would confer a protective effect” on fibroid tumor development by minimizing exposure to environmental pollutants as much as possible.

Okay, so a plant-based diet may be best, but is there a plant in particular that has been shown to be particularly powerful?

Plant-based compounds with disease-preventive properties, dietary phytochemicals are found in whole grains, fruits, vegetables, beans, split peas, chickpeas, and lentils, herbs, spices, nuts, and certain beverages. As I discuss in my video The Best Food for Fibroids, we know they can help regulate the initiation, promotion, and spread of cancerous tumors, so what about benign tumors like fibroids? Most anti-cancer drugs on the market now were originally derived from plants or plant products, so why not try to use plants to target the inflammation or blood supply of fibroids? Might fibroids be a consequence of chronic inflammation within the body? We know that women with fibroids are more likely to eat more beef and ham, and fewer fruits and green vegetables, but whole plant foods don’t just have anti-inflammatory effects but antioxidant effects as well. “If the generation of free radicals exceeds the protective effects of antioxidants, oxidative damage will occur,” which has been implicated in a variety of disease states, including gynecological conditions such as fibroids. 

If you collect fresh fibroids, as well as normal uterine tissue from hysterectomy surgeries, the fibroid cells have significantly fewer antioxidant enzymes, as you can see at 1:20 in my video, so might antioxidant-rich foods help? Well, if you drip some strawberries onto cells in a petri dish, you can apparently kill of some fibroid tumor cells, while leaving normal uterus cells alone. But, what good does that do us? That’s only relevant if we can show those strawberry compounds get absorbed through our gut and achieve high enough concentrations in uterine tissue. The same with curcumin, the component of the spice turmeric. One of its so-called “miraculous” properties is suppressing the growth of uterine fibroid cells, but, again, that was just in vitro. Yes, an inhibitory effect was found and at concentrations that don’t compromise the growth of normal, regular uterine tissue, but my patients are people, not petri dishes. 

It’s pretty neat to find out what happens to human fibroid cells as you drip higher and higher concentrations of green tea compounds on them in a test tube, as you can see for yourself at 2:19 in my video, but I care less about what happens in vitro or in mice, whether or not they have any clothes on—one study looked at “a nude mice model”—but there were no randomized, controlled clinical studies until 2013. 

Subjects were randomized to green tea extract or placebo for four months. In the placebo group, fibroid volume increased by 24 percent. That’s what fibroids do; they continue to grow. However, those randomized to the green tea group showed a reduction in total fibroid volume—and not just by a little. There was a dramatic decrease, shrinking by almost a third, which is a highly significant difference, as you can see at 3:02 in my video. Okay, but did the women feel any better? Yes, they experienced a dramatic decrease in symptom severity, as well. Month after month, nothing much happened in the placebo group, but those taking the pills that looked the same but happened to contain green tea compounds had consistent improvement and felt lessening symptoms, each month better than the last, as well as an improved health-related quality of life, month after month, that was significantly better than control. What’s more, their blood counts got better too. With all that continued excess blood loss every month, the blood levels kept decreasing in the placebo group, but they reversed in the green tea group. So, anemia also significantly improved, because average blood flow significantly diminished. And, all this—the fibroid shrinkage, less pain, better periods—was achieved with “no adverse effects.” 

So, not only were the results comparable to those for the drugs that are commonly used—again, without the side effects—but the results were also comparable to uterine artery embolization, where they try to cut the blood supply to the fibroid, which is great—unless they accidentally cut the blood supply to the rest of the uterus and cause uterine necrosis, one of many reported major complications. Others include death, not only of the fibroid, but also of the patient, along with other potential complications that may arise from accidentally clogging off non-target arteries. In my book, a side-effect-free solution as good as a more invasive procedure is potentially better than. The researchers conclude that green tea compounds show “promise as a safe and effective therapeutic agent for women with symptomatic UFs [uterine fibroids]. Such a simple, inexpensive, and orally administered therapy can improve women’s health globally.” 

Relatively safe doesn’t mean risk-free, however. Although there were no liver function abnormalities detected, this was a small study. If you give green tea extract pills to a thousand women for a year, like they did in the Minnesota Green Tea Trial for breast cancer, the livers in about 1 in 17 women started to get inflamed and a few became serious. Now, the dose they used in this study was twice that of the fibroid study and it’s not completely clear if the pills were the only cause, but, in general, we should try to avoid extracts and instead get nutrition from foods as grown—or at least from foods as grown that are then dunked in hot water, like green tea. 

The researchers had to use pills in this study, because they wanted it to be a double-blind study and it’s hard to create a placebo tea that looks, smells, and tastes like the real thing. I don’t think we should take green tea extract pills, though. We should drink green tea. The problem is that the dose the researchers used was about 11 cups a day, which would be a lot of caffeine. You could choose decaf, though, and it’s not outside the realm of possibility to drink a couple quarts of tea a day, especially if doing so may shrink your fibroids so much you can keep your uterus. But, for all we know, five cups of tea a day would work or maybe even three cups or one cup. No other dose has been tested, so we just don’t know. But, you can test it in your own life. If you have fibroids, it couldn’t hurt to add a few cups of green tea to your daily diet and see if you start feeling better.

And, for even more on fibroids, see Should Women with Fibroids Avoid Soy? and Talcum Powder and Fibroids.

For more on contaminated herbal products, see Get the Lead Out and Some Ayurvedic Medicine Worse Than Lead Paint Exposure.

I’ve got dozens and dozens of videos on the effects of diet on estrogens, such as:

In health, 

Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live presentations:

Do Cell Phones Cause Brain Tumors?

What does the world’s leading authority on carcinogens have to say about mobile phones?

Do cell phones cause cancer? That’s a question billions of people would like to have answered and one I address in my video Cell Phone Brain Tumor Risk?. That’s why we have the World Health Organization’s International Agency for Research on Cancer (IARC), the recognized authority on determining what is and is not carcinogenic. There are five categories: Group 1 carcinogens are agents that we know with the highest level of certainty do cause cancer in human beings, Group 2A probably cause cancer, Group 2B possibly cause cancer, we’re not sure about agents categorized as Group 3, and Group 4 agents probably don’t cause cancer.

In May 2011, 30 scientists from 14 countries met at the IARC to assess the carcinogenicity of the radiation emitted from cell phones and concluded that, given the limited amount of available evidence, cell phones are “‘possibly carcinogenic to humans’ (Group 2B).” So they’re not classified as a Group 1 carcinogen that’s known definitively to be cancer-causing, like plutonium, or processed meat, or as probable carcinogen, like DDT, Monsanto’s Roundup pesticide, or some regular meat, but they are classified as a possible carcinogen, ranked similarly as preserved vegetables like kimchi. 

Now, this classification was made more than five years ago. Evidence continues to mount, and the latest two 2017 systematic reviews found a 33 percent increase in odds of brain tumors with long-term use and showed 46 percent higher odds for tumors on the phone side of your head—and the reviews included the industry-funded studies that have been accused of being biased and flawed, and underestimating the risk, as opposed to independent studies free from “financial conditioning.” How’s that for a euphemism? Given this, some scientists are pushing to have the IARC reclassify cell phones as probable carcinogens or even bump them all the way up into Group 1, at least for brain cancer and acoustic neuroma, a type of inner ear tumor. 

But the IARC classification for cell phones currently remains at possible carcinogen. What does that mean? What do we do with that information? Well, given the uncertainty, we could follow “the precautionary principle” and use simple personal measures to reduce our exposure, like not putting the phone directly up to our head all the time. Indeed, the “main concern about cell phones is that they are usually held close to the head,” which is considered particularly important for children. There’s no evidence of finger cancer, though, so you can keep texting away. 

Other potential personal recommendations include waiting a moment before putting your cell phone to your ear, if you don’t have a headset, because “when the cell phone establishes a connection, the emission is high.” And don’t fall for those anti-radiation gizmos, those “so-called protection covers,” as they may make things worse by forcing the phone to boost the signal.

Not all agree, however, with this precautionary approach. Employees at two cell phone industry trade organizations emphasize “there are many aspects of human activity that are not ‘totally without adverse health effects,’—for example, transport (including aviation) and hot showers,” so they suggest we should just accept the risk as being worth it. Wait. Hot showers? As in we might scald ourselves or something? In any case, they further suggest that we shouldn’t put forth any recommendations because “such judgment should be made by parents on a personal basis for their own children,” and, if we do put out guidelines or something, people might get nervous and we all know “anxiety itself can have deleterious health consequences.” So, basically, the cell phone industry cares so much about your health that it doesn’t want you worrying your pretty little head.

Nevertheless, all of this is openly discussed in the risk analysis literature. “From a public health perspective, it might be reasonable to provide cell phone users with voluntary precautionary recommendations for their cell phone handling in order to enable them to make informed decisions”—but what if the public can’t handle the truth? We don’t want to freak people out. There’s still “scientific uncertainty” and we don’t want to “foster inappropriate fears.” For example, brain cancer is rare to begin with. You only have about a 1 in 15,000 chance a year of getting a brain tumor,  so even if cell phones double your risk, that would only take you up to a 1 in 7,500 chance. You may be more likely to get killed by a cell phone in the hands of a distracted driver than by cancer. So, whether health authorities want to inform the general public about precautionary possibilities really remains more of a political decision.

For more on cell phones and Wi-Fi, see:

What was that about meat and cancer? See my video Carcinogens in Meat. And, to learn more about the IARC’s decision and the industry’s reaction, see:

What about cancer risk of medical diagnostic radiation? See:

In health,

Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live presentations:

Dr. Gundry’s The Plant Paradox Is Wrong

A book purported to expose “hidden dangers” in healthy foods doesn’t even pass the whiff test.

I started getting emails about The Plant Paradox, a book purporting to expose “the hidden dangers in ‘healthy’ foods that cause disease and weight gain”—foods like beans, whole grains, and tomatoes. Hidden dangers? The author’s talking about lectins in a rehashing of the discredited Blood Type Diet from decades ago. I reviewed it a while ago in my video Blood Type Diet Debunked, but it just keeps coming back. The Plant Paradox was written by an MD, but if you’ve seen my medical school videos including Physicians May Be Missing Their Most Important Tool, you’ll know that is effectively an anti-credential when it comes to writing diet books, basically advertising to the world that they’ve likely received little or no formal training in nutrition. Dr. Atkins was, after all, a cardiologist. Even when we give the benefit of the doubt, the problem is it doesn’t even seem to pass the sniff test, as I discuss in my video Dr. Gundry’s The Plant Paradox Is Wrong.

If lectins are bad, then beans would be the worst, so bean counters would presumably find that bean eaters cut their lives short. But, the exact opposite may be true, with legumes—beans, split peas, chickpeas, and lentils—found to be perhaps “the most important dietary predictor of survival in older people” in countries around the world. As Dan Buettner pointed out in his Blue Zones work, lectin-packed foods are the “cornerstones” of the diets of all the healthiest, longest-lived populations on the planet. Plant-based diets in general and legumes, the most lectin-lush of foods, in particular are a common thread among longevity Blue Zones around the world, as you can see at 1:30 in my video.

If lectins are bad, then whole-grain consumers should be riddled with disease when in fact “whole grain intake is associated with a reduced risk of coronary heart disease,” the number one killer of men and women, “cardiovascular disease, and total cancer, and mortality from all causes” put together. This means that people who eat whole grains tend to live longer and suffer from fewer “respiratory diseases, infectious diseases, diabetes, and all non-cardiovascular, non-cancer causes” to boot. And, this is not only the case in population studies. As I showed in my video Can Oatmeal Help Fatty Liver Disease?, you can randomize people into whole grain interventions and prove cause-and-effect benefits. It’s the same with tomatoes. When you randomize women to a cup and a half of tomato juice or water every day, all that nightshade tomato lectin “reduces systemic inflammation” or has waist-slimming effects, reducing cholesterol as well as inflammatory mediators.

So, when people told me about The Plant Paradox, I thought to myself: Let me guess. He sells a line of lectin-blocking supplements. And, what do you know? His Lectin Shield capsules “assist your body in the fight against lectins” for only $79.95 a month. That’s only about a thousand dollars a year—a bargain for “pleasant bathroom visits.” Then, of course, there are ten other supplements for sale, so for only $8,000 or $9,000 a year, you can lick those lectins. Let’s not forget his skincare line. “Firm + Sculpt” for an extra $120 a month, which is all so much more affordable when you subscribe to his VIP club.

Look, people ask me all the time to comment on a new blog, book, or YouTube video, and I remind them that a hundred thousand peer-reviewed scientific papers on nutrition are published in the medical literature every year and we can barely keep up with those. But because people continually emailed me about this book, I decided I’d give it a chance.  He tells us to “forget everything you thought you knew was true.” (Diet books love saying that.) Okay. Ready? Chapter 1, citation 1: “Eating shellfish and egg yolks dramatically reduces total cholesterol.” What?! Egg yolks reduce cholesterol? What is this citation? I’ve linked the paper he cites on shellfish consumption so you can see it for yourself. By now, you know how these studies go. How do you show a food decreases cholesterol? Remove so much meat, cheese, and eggs that, overall, saturated fat falls—in this case, about 50 percent, as you can see at 4:15 in my video. If you cut saturated fat in half, of course cholesterol levels are going to drop. So, the researchers got a drop in cholesterol after removing meat, cheese, and egg yolks, yet that’s the paper he uses to support his statement that “egg yolks dramatically reduce[d] cholesterol.” That’s unbelievable! That’s the opposite of the truth. As you can see at 4:36 in my video, the truth is if you add egg yolks to people’s diets, their cholesterol goes up. How dare he say otherwise? What’s more, it’s not like he’s spewing some harmless foolishness, like saying the Earth is flat. Heart disease is the number one killer of men and women. His claims could actually hurt people.

So much for my giving him the benefit of the doubt.

This is an unusual article for me. I normally try to stay out of the so-called diet wars and just stick to bringing you the latest science. Roughly 100,000 papers are published on nutrition in the peer-reviewed medical literature every year, and we have a hard enough time keeping up with them, but let me know what you think: Would you like me to allocate time to more of these types of reactive discussions?

You’ll note I never really addressed Dr. Gundry’s thesis about lectins, but I do exactly that in these two videos: How to Avoid Lectin Poisoning and Are Lectins in Food Good or Bad for You?.

Here are links to the videos I alluded to in this article, if you want to learn more:

What else can tomatoes do? See Inhibiting Platelet Activation with Tomato Seeds.

One of the key reasons whole grains may be so beneficial is their effect on our good bacteria. Check out Gut Microbiome: Strike It Rich with Whole Grains and Microbiome: We Are What They Eat to learn more.

In health,

Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live presentations: