Garlic Powder to Lower Lead Levels

There are so-called chelation drugs that can be taken for acute, life-threatening lead poisoning—for instance if your two-year-old swallowed one of the little lead weights her grandma was using while sewing curtains and the doctor happened to miss it on x-ray, so it stayed lodged inside her until she died with a blood lead level of 283 mcg/dcl, a case I discuss in my video Best Foods for Lead Poisoning: Chlorella, Cilantro, Tomatoes, Moringa?.

However, for lower grade, chronic lead poisoning, such as at levels under 45 mg/dL, there were no clear guidance as to whether these chelation drugs were effective. When they were put to the test, the drugs failed to bring down lead levels long term. Even when they worked initially, in dose after dose, the lead apparently continued to seep from the patients’ bones, and, by the end of the year, they ended up with the same lead levels as the sugar pill placebo group, as you can see at 0:50 in my video. It was no surprise, then, that even though blood lead levels dipped at the beginning, researchers found no improvements in cognitive function or development.

Since much of lead poisoning is preventable and the drugs don’t seem to work in most cases, that just underscores the need “to protect children from exposure to lead in the first place.” Despite the medical profession’s “best intentions to do something to help these kids…drug therapy is not the answer.” Yes, we need to redouble efforts to prevent lead poisoning in the first place, but what can we do for the kids who’ve already been exposed?

The currently approved method, these chelating drugs that bind and remove lead from our tissues, “lack[s]…safety and efficacy when conventional chelating agents are used.” So, what about dietary approaches? Plants produce phytochelatins. All higher plants possess the capacity to synthesize compounds that bind up heavy metals to protect themselves from the harmful effects, so what if we ate the plants? “Unlike other forms of treatment (e.g., pharmacotherapy with drugs), nutritional strategies carry the promise of a natural form of therapy that would presumably be cheap and with few to no side effects.” Yes, but would it work when the drugs didn’t?

We had learned that a meal could considerably cut down on lead absorption, but “the particular components of food intake that so dramatically reduce lead absorption” were uncertain at the time. Although the calcium content of the meal appeared to be part of it, milk didn’t seem to help and even made things worse. What about calcium supplements? Some assert that calcium supplements may help in reducing lead absorption in children, but “recommendations…must be based on evidence rather than conviction.” What’s more, those assertions are based in part on studies on rodents, and differences in calcium absorption and balance between rats and humans make extrapolation tricky. What you have to do is put it to the test. Researchers found that even an extra whopping 1,800 mg of calcium per day had no effect on blood lead levels. Therefore, the evidence doesn’t support conclusions that calcium supplements help.

What about whole foods? Reviews of dietary strategies to treat lead toxicity say to eat lots of tomatoes, berries, onions, garlic, and grapes, as they are natural antagonists to lead toxicity and therefore should be consumed on a regular basis. Remember those phytochelatins? Perhaps eating plants might help detoxify the lead in our own bodies or the bodies of those we eat.

These natural phytochelatin compounds work so well that we can use them to clean up pollution. For example, the green algae chlorella can suck up lead and hold onto it, so what if we ate it? If it can clean up polluted bodies of water, might it clean up our own polluted bodies? We don’t know, because we only have studies on mice, not men and women.

So, when you hear how chlorella detoxifies, they’re talking about the detoxification of rat testicles. Yes, a little sprinkle of chlorella might help your pet rat, or perhaps you could give them some black cumin seeds or give them a sprig of cilantro, but when you hear how cilantro detoxifies against heavy metals, I presume you don’t expect the researchers to be talking about studies in rodents. If we’re interested in science protecting our children, not just their pets, we’re out of luck.

The same is true with moringa, tomatoes, flaxseed oil, and sesame seed oil, as well as black grapes, and black, white, green, and red tea. There are simply no human studies to guide us.

Dietary strategies for the treatment of lead toxicity are often based on rodent studies, but, for tofu, at least, there was a population study of people that showed lower lead levels in men and women who ate more tofu. The researchers controlled for a whole bunch of factors, so it’s not as if tofu lovers were protected just because they smoked less or ate less meat, but you can’t control for everything.

Ideally, we’d have a randomized, placebo-controlled study. Researchers would take a group of people exposed to lead, split them into two groups, with half given food and the other half given some kind of identical placebo food, and see what happens. It’s easy to do this with drugs because you just use look-alike sugar pills as placebos so people don’t know which group they’re in, but how do you make placebo food? One way to do disguised food interventions is to use foods that are so potent they can be stuffed into a pill—like garlic. There had been various studies measuring the effects of garlic in rats and looking at garlic as a potential antidote for lead intoxication distributed among different mouse organs, but who eats mouse organs? One animal study did have some direct human relevance, though, looking at the effect of garlic on lead content in chicken tissues. The purpose was to “explore the possible use of garlic to clean up lead contents in chickens which”—like all of us on planet Earth—“had been exposed to lead pollution and consequently help to minimize the hazard” of lead-polluted chicken meat.

And…it worked! As you can see at 1:59 in my video Best Food for Lead Poisoning: Garlic, feeding garlic to chickens reduced lead levels in the “edible mass of chicken” by up to 75 percent or more. Because we live in a polluted world, even if you don’t give the chickens lead and raise them on distilled water, they still end up with some lead in their meat and giblets. But, if you actively feed them lead for a week, the levels get really high. When you give them the same amount of lead with a little garlic added, however, much less lead accumulates in their bodies.

What’s even more astonishing is that when researchers gave them the same amount of lead—but this time waited a week before giving them the garlic—it worked even better. “The value of garlic in reducing lead concentrations…was more pronounced when garlic was given as a post-treatment following the cessation of lead administration”—that is, after the lead was stopped and had already built up in their tissues. We used to think that “the beneficial effect of garlic against lead toxicity was primarily due to a reaction between lead and sulfur compounds in garlic” that would glom on to lead in the intestinal tract and flush it out of the body. But, what the study showed is that garlic appears to contain compounds that can actually pull lead not only out of the intestinal contents, but also out of the tissues of the body. So, the “results indicate that garlic contain chelating compounds capable of enhancing elimination of lead,” and “garlic feeding can be exploited to safeguard human consumers by minimizing lead concentrations in meat….”

If garlic is so effective at pulling lead out of chickens’ bodies, why not more directly exploit “garlic feeding” by eating it ourselves? Well, there had never been a study on the ability of garlic to help lead-exposed humans until…2012? (Actually, I’m embarrassed to say I missed it when the study was first published. That was back when I was just getting NutritionFacts.org up and running. Now that we have staff and a whole research team, hopefully important studies like this won’t slip through the cracks in the future.)

The study was a head-to-head comparison of the therapeutic effects of garlic versus a chelation therapy drug called D-penicillamine. One hundred and seventeen workers exposed to lead in the car battery industry were randomly assigned into one of two groups and, three times a day for one month, either got the drug or an eighth of a teaspoon of garlic powder compressed into a tablet, which is about the equivalent of two cloves of fresh garlic a day. As expected, the chelation drug reduced blood lead levels by about 20 percent—but so did the garlic. The garlic worked just as well as the drug and, of course, had fewer side effects. “Thus, garlic seems safer clinically and as effective,” but saying something is as effective as chelation therapy isn’t saying much. Remember how chelation drugs can lower blood levels in chronic lead poisoning, but they don’t actually improve neurological function?

Well, after treatment with garlic, significant clinical improvements were seen, including less irritability, fewer headaches, and improvements in reflexes and blood pressure, but these improvements were not seen in the drug group. They weren’t seen after treatment with the chelation therapy drug. So, garlic was safer and more effective. “Therefore, garlic can be recommended for the treatment of mild-to-moderate lead poisoning.


 There are also some human studieson vitamin C. Check out Can Vitamin C Help with Lead Poisoning?.

For even more lead videos, see:

To learn more about chlorella, see:

In health,

Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live presentations:

The Foods With the Highest Aspirin Content

The results of a recent aspirin meta-analyses suggesting a reduction of cancer mortality by about one-third in subjects taking daily low-dose aspirin “can justly be called astounding.” Yet the protection from “Western” cancers enjoyed by those eating more traditional plant-centered diets, such as the Japanese, “is even more dramatic.” I examine this in my video Plants with Aspirin Aspirations.

Before the Westernization of their diets, animal products made up only about 5 percent or less of the Japanese diet. At 0:37 in my video, you can see the difference in cancer mortality of U.S. men and women compared with Japanese men and women. “[A]ge-adjusted death rates from cancers of the colon, prostate, breast, and ovary were on the order of 5–10-fold lower in Japan than in the US at that time; mortality from pancreatic cancer, leukemias, and lymphomas was 3–4-fold lower in Japan. But this phenomenon was by no means isolated to Japan; Western cancers were likewise comparatively rare in other societies where “people ate plant-based diets.”

“The cancer protection afforded by lifelong consumption of a plant-based diet, in conjunction with leanness and insulin sensitivity (which tend to be promoted by low-fat plant-based diets)…may be very substantial indeed.” Therefore, a “lifestyle protocol for minimizing cancer risk” may include a whole-food plant-based diet.

If part of this cancer protection arises out of the aspirin phytonutrients in plants, are there any plants in particular that are packed with salicylates? Though salicylic acid, the main active ingredient in aspirin, is “ubiquitously present in fruits and vegetables,” the highest concentrations are found in herbs and spices.

Red chili powder, paprika, and turmeric contain a lot of salicylates, but cumin is about 1 percent aspirin by weight. Eating a teaspoon of cumin is like taking a baby aspirin. (See the table at 1:54 in my video for details on other herbs and spices, and their salicylate content.) “Consequently, populations that incorporate substantial amounts of spices in foods may have markedly higher daily intakes of salicylates. Indeed, it has been suggested that the low incidence of colorectal cancer among Indian populations may be ascribed in part to high exposure to dietary salicylates throughout life from spice consumption.”

“The population of rural India, with an incidence of colorectal cancer which is one of the lowest in the world, has a diet that could be extremely rich in salicylic acid. It contains substantial amounts of fruits, vegetables, and cereals flavored with large quantities of herbs and spices.” Some have proposed it’s the curcumin in the spice turmeric (which I discuss in detail in my video Turmeric Curcumin and Colon Cancer), but it may be the salicylic acid in cumin—and the spicier the better.

A spicy vegetable vindaloo may have four times the salicylates of a milder Madras-style veggie dish. As you can see from the chart at 2:55 in my video, after just one meal, we get an aspirin spike in our bloodstream like we just took an aspirin. So, eating flavor-filled vegetarian meals, with herbs and spices, may be more chemoprotective—that is, more protective against cancer—than regular, blander vegetarian meals.

We may also want to eat organic produce. “Because salicylic acid is a defense hormone of plants, the concentration…is increased when plants become stressed,” like when they are bitten by bugs (unlike pesticide-laden plants). Indeed, soups made from organic vegetables were found to have nearly six times more salicylic acid than soups prepared from conventionally grown ingredients.

We should also choose whole foods. Whole-grain breads, which are high in salicylic acid, contain about 100 times more phytochemicals than white bread: 800 phytochemicals compared to 8.

“Interest in the potential beneficial effects of dietary salicylates has arisen, in part, because of the extensive literature on the disease-preventative effects of Aspirin™. However, it should not be forgotten that plant products found to contain salicylic acid are generally rich sources of other phenolic acids…[and many] also have a marked anti-inflammatory and redox-related bioactivity [that is, antioxidant activity] in mammalian cells. Their potential protective effects should not be overlooked. In this context, the importance of dietary salicylic acid should not perhaps be over emphasised…Indeed, some believe that ‘salicylic acid deficiency’ has important public health implications and that it should be classed as an essential vitamin, namely ‘Vitamin S’.”

What they’re saying is that we should all eat a lot of plants.


If you missed the first two videos in this series, see Should We All Take Aspirin to Prevent Heart Disease? and Should We All Take Aspirin to Prevent Cancer?.

The drug-like anti-inflammatory power of certain plant foods may make them a risky proposition during pregnancy. See Caution: Anti-Inflammatory Foods in the Third Trimester.

Herbs and spices not only have some of the most anti-inflammatory properties, but they also are well-rounded protectants. See:

In health,
Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live presentations: